Objective: To assess the anxiety, depression and cortisol level in submariners. Subjects and methods: A cross-sectional study was done in Vietnamese submariners. Anxiety was assessed by Spielberger questionnaire, depression was assessed by Beck questionnaire. | JOURNAL OF MILITARY PHARMACO-MEDICINE No7-2015 INITIAL STUDY of ANXIETY, DEPRESSION AND PLASMA CORTISOL IN SUBMARINERS Nguyen Hoang Luyen*; Nguyen Tung Linh* Nguyen Hoang Thanh**; Nguyen Minh Phuong* SUMMARY Objective: To assess the anxiety, depression and cortisol level in submariners. Subjects and methods: A cross-sectional study was done in Vietnamese submariners. Anxiety was assessed by Spielberger questionnaire, depression was assessed by Beck questionnaire. These tests were conducted in submariners a day before training at sea. Cortisol level was assessed before and after training at sea and automatically analysed by Architect Plus CI16200 Biochemical Analyser. Result: Submariners suffer from T-Anxiety at moderate level with mean score ± . Prevalence of moderate T-Anxiety was . The mean score of depression was ± , the depression was found in of submariners. The prevalence of depression among job groups were significantly defferent (p Table 1 showed that the anxiety level of submariners at particular time was low with mean score 21 ± . The number of submariners with mild anxiety was . There was no case of pathological anxiety. The differences of S-Anxiety among job groups were not significant (p > ). Table 2: T-Anxiety by Spielberger questionnaire (n = 123). JOB GROUP Navigator Mechanic, engine personnel n % n % n % n % n % n % Mild anxiety 7 12 2 3 2 26 Moderate anxiety 19 34 5 5 24 87 Severe anxiety 0 0 5 0 0 3 1 9 CLASSIFICATION Cook, medical, chemical personnel Gunners, torpedo personnel TOTAL Yeoman, sonar, radar personnel 21 JOURNAL OF MILITARY PHARMACO-MEDICINE No7-2015 Pathological anxiety 0 0 1 0 0 0 0 0 0 1 Total 26 100 52 100 7 100 11 100 27 100 123 100 Mean score ± p > The mean score of T-Anxiety of submariners was