Từ bột khô rễ cây Xuân hoa đỏ, Pseuderanthemum carruthersii (Seem.) Guill. var. atropurpureum (Bull.) Fosb., họ Ô rô (Acanthaceae), đã cô lập được bốn lignan, đó là: (+)-eudesmin (1), (+)-magnolin (2), (+)-syringaresinol (3) và (+)-episyringaresinol (4). Cấu trúc của các hợp chất này được xác định bằng các phương pháp phổ nghiệm và so sánh với tài liệu tham khảo. Các hợp chất này được cô lập lần đầu tiên trong chi Pseuderanthemum. | Science & Technology Development, Vol 14, 2011 FOUR LIGNANS FROM ROOT OF PSEUDERANTHEMUM CARRUTHERSII (SEEM.) GUILL. VAR. ATROPURPUREUM (BULL.) FOSB. Vo Thi Nga(1), Nguyen Phi Linh(2), Nguyen Hoang Minh Nhut(2), Nguyen Kim Phi Phung(2), Nguyen Ngoc Suong(2) (1) University of Technical Education– HCM city (2) University of Science, VNU-HCM (Manuscript Received on January 24th 2011, Manuscript Revised October 25th 2011) ABSTRACT: Four lignans were isolated from the dried root of Pseuderanthemum carruthersii (Seem.) Guill. var. atropurpureum (Bull.) Fosb. (Acanthaceae), including (+)-eudesmin (1), (+)-magnolin (2), (+)-syringaresinol (3) and (+)-episyringaresinol (4). Their chemical structures were elucidated by spectroscopic methods as well as comparing with data in the literature. These substances were isolated for the first time from this genus. Key words: Pseuderanthemum, lignan, eudesmin, magnolin, syringaresinol, episiringaresinol. wound.[1] It has not yet much been chemically INTRODUCTION studied. In this paper, the isolation of four var. lignans from the root of this plant and the atropurpureum (Bull.) Fosb. (Figure 1) has structure elucidation of these compounds were been used in traditional medicine to heal the reported. P. carruthersii Trang 12 (Seem.) Guill. TAÏP CHÍ PHAÙT TRIEÅN KH&CN, TAÄP 14, SOÁ T2 - 2011 Figure 1. Pseuderanthemum carruthersii (Seem.) Guill. var. atropurpureum (Bull.) Fosb. EXPERIMENTAL Chemistry, University of Science, National University – HCM City. General experimental procedures The NMR spectra were measured on a Bruker Avance spectrometer, at 500 MHz for 1 H-NMR and 125 MHz for 13C-NMR. The HR- ESI-MS were recorded on a HR-ESI-MS MicroOTOF–Q mass spectrometer. The above spectra were performed in the Center of Analysis, University of Science, National University – HCM City. Optical rotations of all samples were measured on a KRUSS digital polarimeter. Extraction and .
