This lecture includes these contents: Rapid critical appraisal using gate, the gate frame, cross sectional study, clinical use of a diagnostic test, exposure & comparison groups,. Invite you to consult this lecture. | Medical evidence increasing at epidemic rates: we all need EBP skills to keep up-to-date Bastian, Glasziou, Chalmers (2010) 75 Trials and 11Systematic Reviews a Day: How Will We Ever Keep Up? PLoS Med 7(9) Medical evidence increasing at epidemic rates: we all need EBP skills to keep up-to-date approx 75 new trials published every day Bastian, Glasziou, Chalmers (2010) 75 Trials and 11Systematic Reviews a Day: How Will We Ever Keep Up? PLoS Med 7(9) Medical evidence increasing at epidemic rates: we all need EBP skills to keep up-to-date MEDLINE 2010 2,000 articles / day approx 75 new trials published every day Bastian, Glasziou, Chalmers (2010) 75 Trials and 11Systematic Reviews a Day: How Will We Ever Keep Up? PLoS Med 7(9) About 1/3 of worthwhile evidence is eventually refuted or attenuated About 10% of published evidence is worth reading About 1/2 of relevant evidence is not implemented Take out cartoon Rapid critical appraisal using GATE Rod Jackson University of Auckland, . | Medical evidence increasing at epidemic rates: we all need EBP skills to keep up-to-date Bastian, Glasziou, Chalmers (2010) 75 Trials and 11Systematic Reviews a Day: How Will We Ever Keep Up? PLoS Med 7(9) Medical evidence increasing at epidemic rates: we all need EBP skills to keep up-to-date approx 75 new trials published every day Bastian, Glasziou, Chalmers (2010) 75 Trials and 11Systematic Reviews a Day: How Will We Ever Keep Up? PLoS Med 7(9) Medical evidence increasing at epidemic rates: we all need EBP skills to keep up-to-date MEDLINE 2010 2,000 articles / day approx 75 new trials published every day Bastian, Glasziou, Chalmers (2010) 75 Trials and 11Systematic Reviews a Day: How Will We Ever Keep Up? PLoS Med 7(9) About 1/3 of worthwhile evidence is eventually refuted or attenuated About 10% of published evidence is worth reading About 1/2 of relevant evidence is not implemented Take out cartoon Rapid critical appraisal using GATE Rod Jackson University of Auckland, NZ August 2011 Graphic Approach To Evidence Based Practice Graphic Approach To Epidemiology Graphic Appraisal Tool for Epidemiological studies the GATE frame the shape of every epidemiological study My whole career in one picture – the epidemiological paradigm British doctors non-smokers smokers Lung cancer yes no 5 years smoking status measured Longitudinal (cohort) study British doctors non-smokers smokers Lung function normal abnormal smoking status measured Cross-sectional study British doctors placebo aspirin Myocardial infarction yes no 5 years Randomised to aspirin or placebo RCT Middle-aged US women Breast cancer Mammogram negative yes no Test applied Clinical use of a diagnostic test Mammogram positive Middle-aged US women no Breast cancer Breast cancer mammogram positive negative Diagnostic test accuracy study GATE: Graphic Appraisal Tool for Epidemiological studies 1 picture, 2 formulas & 3 acronyms Aim was to develop a simple, generic, and
