The particle size can be tuned in the range of nm by varying synthetic conditions. The obtained particles with small DLS size (less than 21 nm) are ready to disperse and stable in aqueous solution for weeks without any surface modification. | Tạp chí Khoa học và Công nghệ 54 (1) (2016) 123-132 ONE STEP SYNTHESIS OF WATER-DISPERSIBLE CoFe2O4 MAGNETIC NANOPARTICLES USING TRIETHYLENETETRAMINE AS SOLVENT AND STABILISING LIGAND Kieu T. B. Ngoc1, Phạm V. Luyen2, Nguyen C. Khang1, Pham H. Nam3, Do H. Manh3, Pham V. Vinh2, Pham V. Hung2, Le T. Lu4, * 1 2 Nano Center-Hanoi University of Education, 136 Xuan Thuy, Cau Giay, Hanoi Faculty of Physics, Hanoi University of Education, 136 Xuan Thuy-Cau Giay, Hanoi 3 4 Institute of Materials Science-VAST, 18 Hoang Quoc Viet, Cau Giay, Hanoi Institute for Tropical Technology-VAST, 18 Hoang Quoc Viet, Cau Giay, Hanoi * Email: ltlu_itims@ Received: 30 March 2015; Accepted for publication: 12 July 2015 ABSTRACT Magnetic CoFe2O4 nanoparticles were synthesised by one step synthetic method through thermal decomposition of Co and Fe precursors in triethylenetetramine solvent at high temperature. The advantage of this method is the ability to make monodisperse nanoparticles with high water-dispersibility and stability. The particle size can be tuned in the range of nm by varying synthetic conditions. The obtained particles with small DLS size (less than 21 nm) are ready to disperse and stable in aqueous solution for weeks without any surface modification. Keywords: magnetic nanoparticles, water-dispersible, biomedicine, one step synthetic method. 1. INTRODUCTION Magnetic nanomaterials have wildely received attentions due to their diverse applications in the fields such as information technology [1], environmental treatment [2], catalysis [3, 4] and particularly in biomedicine [5]. In biomedicine, the magnetic nanoparticles can be used for biological separation, targeted drug delivery, or as contrast enhancers for magnetic resonance imaging (MRI) [6]. To date, synthetic strateries of nanoparticles in organic solvents at elevated temperatures under the presence of hydrophobic surfactant(s) are widely used for their ability to prepare monodisperse .
