This study investigates PAHs content in road dust of Hanoi metropolis, Vietnam. The samples were colected from the roads around city and analyzed by gas chromatography mass spectrometry (GC/MS). The total PAHs mass concentration ranges from µg/kg to 5588,16 µg/kg, with the mean of 356,24 µg/kg in which HMW accounted up 70 % and LMW made up 30 %. | Journal of Science and Technology 54 (2A) (2016) 27-34 HUMAN HEALTH HAZARD OF POLYCYCLIC AROMATIC HYDROCARBON IN ROAD DUST IN HA NOI METROPOLIS Vo Thi Le Ha1, *, Nguyen Thi Thu Hien1, Minoru Yoneda2 1 School for environmental Science and Technology, Hanoi Univesity of Sience and Technology, 01 Dai Co Viet Road, Hanoi, Vietnam 2 Kyoto University, KyotoDaigakuKatsura, Nishikyo-ku, Kyoto 615-8540, Japan * Email: Received: 6 May 2016; Accepted for publication: 20 June 2016 ABSTRACT This study investigates PAHs content in road dust of Hanoi metropolis, Vietnam. The samples were colected from the roads around city and analyzed by gas chromatography mass spectrometry (GC/MS). The total PAHs mass concentration ranges from µg/kg to 5588,16 µg/kg, with the mean of 356,24 µg/kg in which HMW accounted up 70 % and LMW made up 30 %. The toxic equivalence factors (TEFs), mutagenic potency equivalent factors (MEFs) and the incremental lifetime cancer risk (ILCR) methodologies were applied to evaluate human exposure to carcinogenic PAHs sources. Carcinogenic equivalents (BaP-TEQ) and mutagenic equivalents (BaP-MEQ) were calculated from the potency relative to BaP (TEF) and BaP (MEF). The value of BaP-TEQ for 8 PAHs varied from µg/kg to µg/kg with mean of µg/kg, while the value of BaP-MEQ ranged µg/kg to µg/kg with mean of µg/kg. Basing on ILCRs model, the total cancer risk for children and adults was up to ×10-5 and ×10-5, posing a moderate potential cancer risk, respectively. Key words: Heath risk, road dust, PAHs, ILCR, Hanoi metropolis 1. INTRODUCTION Polycyclic aromatic hydrocarbons (PAHs) are known as a group of organic compounds containing two or more fused aromatic rings. They can enter into the environment via pyrogenic and petrogenic sources [1, 2]. Pyrogenic sources are those where PAHs are generated by high temperature combustion of fossil (coal and petroleum) such as vehicle exhaust particles .