Part 1 book “Applied epidemiologic principles and concepts - Clinicians’ guide to study design and conduct” has contents: Epidemiologic research conceptualization and rationale, clinical research proposal development and protocol, epidemiology, historical context, and measures of disease occurrence and association, and other contents. | Applied Epidemiologic Principles and Concepts This book provides practical knowledge to clinicians and biomedical researchers using biological and biochemical specimen/samples in order to understand health and disease processes at cellular, clinical, and population levels. The concepts and techniques provided will help researchers design and conduct studies, then translate data from bench to clinics in an attempt to improve the health of patients and populations. This book presents the extreme complexity of epidemiologic research in a concise manner that will address the issue of confounders, thus allowing for more valid inferences and yielding results that are more reliable and accurate. Laurens Holmes Jr. was trained in internal medicine, specializing in immunology and infectious diseases prior to his expertise in epidemiology-withbiostatistics. Over the past two decades, Dr. Holmes had been working in cancer epidemiology, control, and prevention. His involvement in chronic disease epidemiology, control, and prevention includes signal amplification and stratification in risk modeling and health disparities in hypertension, and diabetes mellitus with large legacy (preexisting . National Health Statistics Center) data. Applied Epidemiologic Principles and Concepts Clinicians’ Guide to Study Design and Conduct Laurens Holmes Jr., MD, DrPH First published 2018 by Routledge 711 Third Avenue, New York, NY 10017 and by Routledge 2 Park Square, Milton Park, Abingdon, Oxon, OX14 4RN Routledge is an imprint of the Taylor & Francis Group, an informa business © 2018 Taylor & Francis The right of L. Holmes to be identified as author of this work has been asserted by him in accordance with sections 77 and 78 of the Copyright, Designs and Patents Act 1988. All rights reserved. No part of this book may be reprinted or reproduced or utilised in any form or by any electronic, mechanical, or other means, now known or hereafter invented, .