Part 2 book “Robbins basic pathology” has contents: Hematopoietic and lymphoid systems, oral cavity and gastrointestinal tract, kidney and its collecting system, liver, gallbladder, and biliary tract, male genital system and lower urinary tract, endocrine system, central nervous system, and other contents. | See Targeted Therapy available online at Hematopoietic and Lymphoid Systems C H A P T E R 11 C H A P T E R CO N T E N T S RED CELL DISORDERS 408 Anemia of Blood Loss: Hemorrhage 409 Hemolytic Anemias 409 Hereditary Spherocytosis 410 Sickle Cell Anemia 411 Thalassemia 413 Glucose-6-Phosphate Dehydrogenase Deficiency 416 Paroxysmal Nocturnal Hemoglobinuria 417 Immunohemolytic Anemias 417 Hemolytic Anemias Resulting from Mechanical Trauma to Red Cells 418 Malaria 418 Anemias of Diminished Erythropoiesis 419 Iron Deficiency Anemia 420 Anemia of Chronic Disease 421 Megaloblastic Anemias 422 Aplastic Anemia 424 Myelophthisic Anemia 424 Polycythemia 425 WHITE CELL DISORDERS 425 Non-Neoplastic Disorders of White Cells 425 Leukopenia 425 Reactive Leukocytosis 426 Reactive Lymphadenitis 427 Neoplastic Proliferations of White Cells 428 Lymphoid Neoplasms 429 Myeloid Neoplasms 444 Histiocytic Neoplasms 449 Thrombocytopenia 452 Immune Thrombocytopenic Purpura 452 Heparin-Induced Thrombocytopenia 453 Thrombotic Microangiopathies: Thrombotic Thrombocytopenic Purpura and Hemolytic Uremic Syndrome 453 Coagulation Disorders 454 Deficiencies of Factor VIII–von Willebrand Factor Complex 454 DISORDERS THAT AFFECT THE SPLEEN AND THYMUS 456 Splenomegaly 456 Disorders of the Thymus 456 Thymic Hyperplasia 457 Thymoma 457 BLEEDING DISORDERS 449 Disseminated Intravascular Coagulation 450 The hematopoietic and lymphoid systems are affected by a wide spectrum of diseases. One way to organize these disorders is based on whether they primarily affect red cells, white cells, or the hemostatic system, which includes platelets and clotting factors. The most common red cell disorders are those that lead to anemia, a state of red cell deficiency. White cell disorders, by contrast, are most often associated with excessive proliferation, as a result of malignant transformation. Hemostatic derangements may result in hemorrhagic .
