Their structures were elucidated using 1-D and 2-D NMR techniques and by comparison with the literature data. This is the first time to isolate these compounds from Aralia hiepiana. | Vietnam Journal of Science and Technology 56 (4A) (2018)259-265 FLAVONOIDS FROM THE LEAVES OF ARALIA HIEPIANA Nguyen Thi Dieu Thuan1,*, Nguyen Thi Thu Hien1,2, Tran Minh Hao3, Pham Van Huyen1, Nguyen Huu Toan Phan1,2 1 Tay Nguyen Institute for Scientific Research, Vietnam Academy of Science and Technology (VAST), 116 Xo Viet Nghe Tinh, DaLat 2 Graduate University of Science and Technology, VAST, 18 Hoang Quoc Viet, Cau Giay, HaNoi 3 Dalat University, 1 Phu Dong Thien Vuong, Da Lat * Email: ngtdthuan@ Received:23 July 2018; Accepted for publication: 30 September 2018 ABSTRACT Aralia hiepiana & Lowry (Araliaceae), a new species from southern Vietnam, is described and illustrated by J. Wen & Lowry in 2002. Up to now, there are not any chemical data from this endemic species. By various chromatography methods, fiveflavonoids namely kaempferitrin (1), kaempferol 3-O-β-D-glucopyranosyl-7-O- -L-rhamnopyranoside(2), kaempferol (3), quercetin (4),andapigetrin (5) were isolated from the methanol extract of leaves of Aralia hiepianacollected in Da Lat, Lam Dong province. Their structures were elucidated using 1-D and 2-D NMR techniques and by comparison with the literature data. This is the first time to isolate these compounds from Aralia hiepiana. Keywords:Aralia hiepiana,Araliaceae, kaempferitrin, kaempferol3-O-β-D-glucopyranosyl-7-O -L-rhamnopyranoside, kaempferol, quercetin, apigetrin. 1. INTRODUCTION Aralia genus belonging to Araliaceae family, comprises of 74 species over the world [1] and15 species in Vietnam [2]. Several species have been used as in traditional herbal medicine for the treatment of gastric ulcer, hepatitis, rheumatic, arthritis, cancer and other diseases [2]. There have been many publications on the chemical compositions and biological activity of the Aralia species such as Aralia elata [3, 4], A. taibaiensis [5, 6], and A. armata [7]. Compounds mainly found in this genus were triterpenoid saponin and flavonoid glycosides .
