Nanomaterials-based diagnostics have tremendous advantages over other conventional diagnostic systems in terms of sensitivity, specificity, and portability owing to the unique intrinsic properties of nanomaterials. Thus, there is a substantial need to develop and employ a broad spectrum of nanomaterials for biological and diagnostic applications. | Turkish Journal of Biology Turk J Biol (2017) 41: 673-699 © TÜBİTAK doi: Review Article Hybrid nanomaterial: biocolloidals 1, 2 3 Numan GÖZÜBENLİ *, Emir YASUN , Nihat DİLSİZ Department of Molecular Biology and Genetics, Faculty of Arts and Sciences, Harran University, Şanlıurfa, Turkey 2 Department of Mechanical Engineering and Biological Nanostructures Laboratory, California NanoSystems Institute (CNSI), University of California, Santa Barbara, CA, USA 3 Department of Molecular Biology and Genetics, Faculty of Engineering and Natural Sciences, İstanbul Medeniyet University, İstanbul, Turkey 1 Received: Accepted/Published Online: Final Version: Abstract: Nanomaterials-based diagnostics have tremendous advantages over other conventional diagnostic systems in terms of sensitivity, specificity, and portability owing to the unique intrinsic properties of nanomaterials. Thus, there is a substantial need to develop and employ a broad spectrum of nanomaterials for biological and diagnostic applications. In this review, we focus on nanomaterials-assisted disease diagnosis utilizing different techniques such as photoluminescence, colorimetry, fluorescence, electrochemistry, microarray methods, surface plasmon resonance, and surface-enhanced Raman spectroscopy. In these techniques, different nanomaterials, including but not limited to gold and silver materials, metal oxides, and semiconductors, were employed according to their all-purpose chemical and physical properties. As the new properties of nanomaterials are discovered, their contributions to nanobiotechnology applications are vastly increased. In this review, the features of the selected nanobiomaterials, biological tag-modified nanomaterials, and their outstanding applications for the detection of specific biotargets have been summarized according to the latest studies. Nanomaterials contribute to the fields of .
