Aqueous and methanol extracts of Salvadora persica L., a plant used in Iraq for oral hygiene, was investigated for its antimicrobial activities against 7 isolated oral pathogens: Staphylococcus aureus, Streptococcus mutans, Streptococcus faecalis, Streptococcus pyogenis, Lactobacillus acidophilus, Pseudomonas aeruginosa, and Candida albicans using disc diffusion and micro-well dilution assays. | Turk J Biol 32 (2008) 57-62 © TÜB‹TAK In Vitro Antimicrobial Activity of Salvadora persica L. Extracts Against Some Isolated Oral Pathogens in Iraq Firas A. AL-BAYATI, Khudir D. SULAIMAN Department of Biology, College of Education, University of Mosul, IRAQ Received: Abstract: Aqueous and methanol extracts of Salvadora persica L., a plant used in Iraq for oral hygiene, was investigated for its antimicrobial activities against 7 isolated oral pathogens: Staphylococcus aureus, Streptococcus mutans, Streptococcus faecalis, Streptococcus pyogenis, Lactobacillus acidophilus, Pseudomonas aeruginosa, and Candida albicans using disc diffusion and micro-well dilution assays. According to both antimicrobial assays the aqueous extract inhibited all isolated microorganisms, especially the Streptococcus species, and was more efficient than the methanol extract, which was resisted by Lacto. acidophilus and Ps. aeruginosa. The strongest antibacterial activity was observed using the aqueous extract against Strep. faecalis (zone of inhibition: mm; MIC: mg/ml). Both extracts had equal antifungal activity against C. albicans based on the turbidity test (MIC: mg/ml). Key Words: Antimicrobial activity, medicinal plants, Salvadora persica, oral hygiene tool Salvadora Persica L. Bitkisinin Ekstrelerinin Irak’ta ‹zole Edilen Baz› A¤›z Patojenleri Üzerine Etkisi Özet: Irak’ta a¤›z hijeninde kullan›lan Salvadora persica L. bitskisinin s›v› ve methanol özütü yedi a¤›z patojenine olan Staphylococcus aureus, Streptococcus mutans, Streptococcus faecalis, Streptococcus pyogenis, Lactobacillus acidophilus, Pseudomonas aeruginosa ve Candida albicans bakteri üzerine antimikrobial aktivitesi disk diffüzyon ve mikro-well seyreltme yöntemi ile çal›fl›lm›flt›r. S›v› özüt izole edilen ekstrakt bütün mikroorganizmalar›n özellikle Streptococcus türlerinin büyümesini engellemifl ve methanol ekstraktan daha etkili olmufltur. L. acidophilus ve P. aeruginosa methanol özüte dirençli
