This study was carried out to investigate whether plant growth regulators (PGRs) could affect lipid peroxidation (Malondialdehyde = MDA level) in erythrocyte, muscle, liver, heart and kidney tissue. Eighteen Sprague-Dawley albino rats were divided into three experimental groups: control and PGR-treated (indoleacetic acid and kinetin). | Turk J Biol 26 (2002) 193-196 © TÜB‹TAK Effects of Indoleacetic Acid and Kinetin on Lipid Peroxidation Levels in Various Rat Tissues ‹smail ÇEL‹K, Yasin TÜLÜCE, Necati ÖZOK Department of Biology, Faculty of Sciences and Arts, Yüzüncü Y›l University, Van - TURKEY Received: Abstract: This study was carried out to investigate whether plant growth regulators (PGRs) could affect lipid peroxidation (Malondialdehyde = MDA level) in erythrocyte, muscle, liver, heart and kidney tissue. Eighteen Sprague-Dawley albino rats were divided into three experimental groups: control and PGR-treated (indoleacetic acid and kinetin). Seventy-five ppm of PGRs, indoleacetic acid (IAA), and kinetin were administered orally to 6 rats ad libitum for 25 days. The hormone treatments caused different effects on the level of malondialdehyde (MDA) to those of the control rats. According to the results, while liver and kidney MDA levels were increased significantly by IAA administration in rats, kinetin did not affect the MDA levels in erythrocyte and other tissues. It was concluded that IAA might affect lipid peroxidation in animals at subacute treatment. Key Words: Plant growth regulators, Malondialdehyde, in vivo ‹ndolasetik asit ve Kinetinin S›çanlar›n Çeflitli Dokular›nda Lipid Peroksidasyon Düzeyi Üzerine Etkisi Özet: Bu çal›flmada, subletal konsantrasyonda laboratuar flartlar›nda s›çanlar›n kas, karaci¤er, kalp, böbrek ve eritrosit malondialdehit (MDA) düzeyi üzerine indolasetik asit (IAA) ve kinetinin etkilerinin araflt›r›lmas› amaçlanmaktad›r. S›çanlar deney süresince içebildi¤ince 75 ppm'lik IAA ve kinetin uygulamas›na 25 gün maruz b›rak›ld›. Hormon uygulamalar›n›n çeflitli dokulardaki MDA düzeyi üzerine farkl› etkilere neden olduklar› gözlendi. Sonuçlara göre; karaci¤er ve böbrek MDA düzeyi IAA taraf›ndan önemli derecede artt›r›l›rken, kinetin eritrosit ve doku MDA düzeyi üzerinde etkisiz bulundu. Sonuç olarak; IAA’n›n subkronik uygulamalarda toksik etkilere sahip oldu¤u
