The effects of chronic treatment with small sublethal doses (20 mg/kg and 50 mg/kg) of Teucrium polium ethanolic extract were investigated on the hematological and biochemical composition of the blood, histopathology of the liver and kidney, and fertility in the rat. | Turk J Biol 26 (2002) 65-71 © TÜB‹TAK The Chronic Effects of Teucrium polium on Some Blood Parameters and Histopathology of Liver and Kidney in the Rat Khaled KHLEIFAT, Jumah SHAKHANBEH, Khaled TARAWNEH Department of Biology, Faculty of Science University of Mu’tah, . Box 7 Karak - JORDAN Received: Abstract: The effects of chronic treatment with small sublethal doses (20 mg/kg and 50 mg/kg) of Teucrium polium ethanolic extract were investigated on the hematological and biochemical composition of the blood, histopathology of the liver and kidney, and fertility in the rat. Hematological and biochemical parameters of the blood, as well as sperm count, morphology and motility were normal after 6 weeks of herbal treatment. However, blood urea (P to just ). Similarly, Table 2 shows the various biochemical parameters of the blood in the four groups of rats. However, blood urea (P . Moreover, the percentage of sperm with normal morphological K. KHLEIFAT, J. SHAKHANBEH, K. TARAWNEH Hematological parameters Non-treated Olive oil RBCs X106/ mm3 ± ± ± ± WBCs X103/ mm3 ± ± ± ± Platel. X103/ mm3 ± ± ± ± HCT % ± ± ± ± 3 Lym X10 /mm ± ± ± ± Mon X103/mm3 ± ± ± ± Gran X103/mm3 ± ± ± ± % Lymphocytes ± ± ± ± % Monocytes ± ± ± ± % Granulocytes ± ± ± ± MCV (mm3) ± ± ± ± MCH (pg) ± ± ± ± MCHC (g/dl) ± ± ± ± RDW % ± ± ± ± MPV (mm3) ± ± ± ± PDW .
