The effects of a sublethal concentration of three plant growth regulators (PRGs) on serum enzymes in rats were investigated under laboratory conditions. 100-ppm of PRGs, indoleacetic acid (IAA), indolebutiric acid (IBA) and kinetin were administered orally to 8 rats ad libitum for 3 weeks. | Turk J Biol 26 (2002) 73-76 © TÜB‹TAK Effects of Subchronic Treatment of Some Plant Growth Regulators on Serum Enzyme Levels in Rats ‹smail ÇEL‹K Yüzüncü Y›l University, Faculty of Arts and Sciences, Deparment of Biology, Van - TURKEY Hanefi ÖZBEK Yüzüncü Y›l University, Faculty of Medicine,Deparment of Pharmacology, Van - TURKEY Yasin TÜLÜCE Yüzüncü Y›l University, Faculty of Arts and Sciences, Deparment of Biology, Van - TURKEY Received: Abstract: The effects of a sublethal concentration of three plant growth regulators (PRGs) on serum enzymes in rats were investigated under laboratory conditions. 100-ppm of PRGs, indoleacetic acid (IAA), indolebutiric acid (IBA) and kinetin were administered orally to 8 rats ad libitum for 3 weeks. The hormon treatments caused different effects on the level of serum alanin aminotransferase (ALT), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), amylase and creatine phosphokinase (CPK) in comparison to those of control rats. According to the results, while the levels of LDH and CPK were increased significantly by IBA, the levels of AST, LDH and CPK were increased significantly by IAA. In addition, the levels of AST, LDH and CPK were increased significantly by kinetin. In conclusion, these chemicals have toxicological effects on the animals in subchronic treatment. Key Words: Plant Growth Regulators, Serum Enzymes, Rat Baz› Bitki Büyüme Düzenleyicilerinin Subkronik Uygulanmas›n›n S›çanlar›n Serum Enzim Düzeyleri Üzerine Etkisi Özet: Baz› bitki büyüme düzenleyicilerinin subletal konsantrasyonda laboratuar flartlar›nda s›çanlar›n serum enzim düzeyleri üzerine etkileri araflt›r›ld›. Sekiz adet difli s›çandan oluflan gruplar deneme boyunca içebildi¤ince 100 ppm'lik IAA, IBA ve kinetin uygulamas›na üç hafta maruz b›rak›ld›. Sonuçlar gösterdi ki; bu büyüme düzenleyicileri serumun alanin aminotransferaz (ALT), aspartate aminotransferaz (AST), lactate dehidrogenaz (LDH), amilaz ve kreatine fosfokinaz (CPK) .
