Research on the risk factors of liver cancer, particularly HBV infection is necessary for preventing liver cancer and to reduce the prevalence of this cancer in future. Objectives: To identify the risk factors among patients with liver cancer in Hue college of Medicine and Pharmacy. Methods: A case-control study was conducted from May 2007 to May 2008 in which there were 40 patients with liver cancer and 40 people without any liver diseases. | JOURNAL OF SCIENCE, Hue University, N0 61, 2010 RESEARCH ON CHRONIC HBV INFECTION AND RISK FACTORS IN PATIENTS WITH LIVER CANCER IN THE HOSPITAL OF HUE COLLEGE OF MEDICINE AND PHARMACY Vo Dang Anh Thu, Nguyen Thi Kim Hoa, Pham Van Linh College of Medicine and Pharmacy, Hue University SUMMARY Research on the risk factors of liver cancer, particularly HBV infection is necessary for preventing liver cancer and to reduce the prevalence of this cancer in future. Objectives: To identify the risk factors among patients with liver cancer in Hue college of Medicine and Pharmacy. Methods: A case-control study was conducted from May 2007 to May 2008 in which there were 40 patients with liver cancer and 40 people without any liver diseases. For each patient, there was a person in the control group has the same age, gender and living areas. Results: (1) The average age of the study subjects was ± in which age ± was the mean for men and age ± for women, 50% of liver cancer patients aged from 45 to 60. The ratio of men to women was 3 to 1. (2) The risk factors of liver cancer include: HBsAg (+) (OR = ), history of alcohol consumption (OR=), drinking frequency (OR=), the volume of alcohol intake (OR=), tobacco consumption (OR = ), familial history of liver cancer (OR = ). (3) The exposure to organic pesticides is not associated with liver cancer (OR=, p>, χ2= ). Conclusion: This research was useful in identifying risk factors of liver cancer. The results from this research will be used to inform the community and future study of the risk factors of liver cancer. 1. Introduction Liver cancer is one of the most common cancers worldwide. This is the fifth most common cause of cancer in men and the eighth most common cause in women. In Vietnam, liver cancer is also a common and serious cancer that affects men more often than women, and which was ranked the third most common cancer in men and the sixth in women. As in many .
