Objectives: To evaluate Helicobacter pylori infection and its relation with severity of cirrhosis, portal hypertension in cirrhotic patients. Subjects and methods: Prospective, cross-sectional descriptive study was carried out on 65 cirrhotic patients at the Digestive Department, 103 Military Hospital. | Journal of military pharmaco-medicine no7-2018 STUDY ON HELICOBACTER PYLORI INFECTION IN CIRRHOTIC PATIENTS Duong Quang Huy*; Hoang Van Quan* SUMMARY Objectives: To evaluate Helicobacter pylori infection and its relation with severity of cirrhosis, portal hypertension in cirrhotic patients. Subjects and methods: Prospective, cross-sectional descriptive study was carried out on 65 cirrhotic patients at the Digestive Department, 103 Military Hospital. Diagnosing and evaluating severity of Helicobacter pylori infection at gastric mucosa by histopathological method. Results: Prevalence of Helicobacter pylori in cirrhotic patients was . Among those, mild Helicobacter pylori infection was predominant with 22/31 () patients. There was no relationship between Helicobacter pylori infection and severity of cirrhosis according to Child-Pugh classification, as well as several signs of portal hypertension in cirrhotic patients. Conclusion: Helicobacter pylori infection was not popular in cirrhotic patients and not impacted by liver dysfunction and portal hypertension. * Keywords: Cirrhosis; Helicobacter pylori infection. INTRODUCTION Cirrhosis is a quite popular disease in many countries in the world, including Vietnam. Its main causes are hepatitis B/C virus infection and alcohol abuse. It tends to increase at present because rate of people who have been infected with hepatitis virus and drink alcohol and beer excessively remains very highly [1]. There are two stages of cirrhosis: Compensated phase is often asymptomatic, followed by decompensated cirrhosis with many complications of liver failure and portal hypertension such as variceal heamorrhage, hepatic encephalopathy, hepatorenal syndrome, hepato-pulmonary syndrome Besides, along with the development of digestive endoscopy for over 30 years, the impact of cirrhosis on the gastrointestinal mucosa is also increasingly recorded such as portal hypertensive gastropathy (PHG), gastric antral vascular ectasia .
