To compare the technical parameters of the radiotherapy plan using 18FDG PET/CT simulations to the plan of using CT simulation in 3D conformal radiation therapy in patients with esophageal cancer. A prospective clinical interventional study was performed on 22 patients who were diagnosed with esophageal cancer and were indicated radiotherapy at Cancer Center, 103 Military Hospital from January 2017 to July 20118. | Journal of military pharmaco-medicine no1-2019 COMPARE 18FDG-PET/CT SIMULATION AND CT SIMULATION IN THE 3D CONFORMAL RADIATION THERAPY ON THE PATIENTS WITH ESOPHAGEAL CANCER Tran Van Ton1; Tran Viet Tien1; Lai Thi Dinh1 SUMMARY 18 Objectives: To compare the technical parameters of the radiotherapy plan using FDG PET/CT simulations to the plan of using CT simulation in 3D conformal radiation therapy in patients with esophageal cancer. Subjects and methods: A prospective clinical interventional study was performed on 22 patients who were diagnosed with esophageal cancer and were indicated radiotherapy at Cancer Center, 103 Military Hospital from January 2017 to July 20118. Results: 18 The length of primary tumors on FDG PET/CT was ± cm, it was ± on CT 18 with p = . Compared to CT simulation, FDG PET/CT reduced primary tumor length in 18 of patients and increased primary tumor length in of patients. FDG PET/CT increased the number of lymph nodes in 50% of patients and decreased in of patients; of the patients had the same number of lymph nodes. The overall average of cumulative 18 3 3 radiation in the nodes on FDG PET/CT was ± cm , it was ± cm on CT 18 with p = . V40 of both lungs on the plan of using FDG PET/CT simulations was ± ; 18 the plan of using CT was ± with p = . Conclusion: The application of FDG PET/CT simulations in 3D conformal radiation therapy help to determine the volume of tumor and lymph nodes more accurately than CT and should be routinely applied in esophageal cancer radiotherapy. 18 * Keywords: Esophageal cancer; FDG PET/CT simulation; 3D conformal radiotherapy. INTRODUCTION In the treatment of esophageal cancer, radiation therapy is an important and effective method. 3D conformal radiotherapy is a modern technique that allows to concentrate high doses of radiation in the tumor and minimizes the dose of radiation to the surrounding .
