In clinical practice, renal dysfunction is common and associated with re-hospitalization and reduced survival in patients with heart failure. Objectives: To determine the prevalence, characteristics of renal function in heart failure patients and to investigate the relationship between reduced renal function with the degree of heart failure, left ventricular ejection fraction, serum BNP. | Journal of military pharmaco-medicine no5-2018 RENAL DYSFUNCTION IN HEART FAILURE PAITIENTS Nguyen Duy Toan*; Le Thi Ngoc Han* Tran Duc Hung *; Nguyen Oanh Oanh* SUMMARY Background: In clinical practice, renal dysfunction is common and associated with re-hospitalization and reduced survival in patients with heart failure. Objectives: To determine the prevalence, characteristics of renal function in heart failure patients and to investigate the relationship between reduced renal function with the degree of heart failure, left ventricular ejection fraction, serum BNP. Methods and results: In 95 patients with heart failure at Department of Cardiology, 103 Military Hospital from 2016 November to 2017 April, of the patients had worsening renal function. Mean NYHA functional class was ± for -1. -2 -1. -2 eGFR > 36 64 22 ± ± < ± 13 () 49 () 33 () ± 3 (6%) 32 (64%) 15 (30%) ± 10 () 17 () 18 (40%) < ± ± ± < Mean age, BNP and NYHA function class of the patients with eGFR < 60 m-2 was higher than that of the patients with eGFR 60 m-2. 1 Figure 1: Distribution of eGFR. The majority of HF patients had eGFR < 60 (). 181 Journal of military pharmaco-medicine no5-2018 Figure 2: Relationship between eGFR and LVEF. The rate of patients with eGFR < 60 -2 in the group LVEF < 50% was almost twice as high as that of the group LVEF ≥ 50%. This difference is statistically significant. (r = ; p < ; eGFR = LVEF + ) Figure 3: The correlation between eGFR and LVEF. There was a significant positive correlation between eGFR and LVEF. The linear regression showed that EF decreased by 1% when the eGFR decreased . 182 Journal of military pharmaco-medicine .
