Mục tiêu nghiên cứu: Mô tả đặc điểm lâm sàng, cận lâm sàng của trẻ mắc bệnh nhiễm toan ống thận. Đối tượng nghiên cứu: Gồm 36 bệnh nhân được chẩn đoán và điều trị bệnh nhiễm toan ống thận tại khoa Thận – lọc máu bệnh viện Nhi trung ương từ tháng 6 năm 2012 đến tháng 7 năm 2017. | Nghiên cứu đặc điểm lâm sàng, cận lâm sàng bệnh nhiễm toan ống thận ở trẻ em VNU Journal of Science: Medical and Pharmaceutical Sciences, Vol. 35, No. 1 (2019) 120-127 Original Article Clinical, Paraclinical Characteristics in Children with Renal Tubular Acidosis Nguyen Thanh Tung1, Nguyen Thu Huong2, Pham Van Dem3,* Nguyen Thi Quynh Huong4 1 Vinh Phuc Pediatric Hospital, 395 Me Linh, Vinh Yen, Vinh Phuc, Vietnam 2 Vietnam National Children’s Hospital, 18/879 La Thanh, Dong Da, Hanoi, Vietnam 3 VNU School of Medicine and Pharmacy, 144 Xuan Thuy, Cau Giay, Hanoi, Vietnam 3 Bach Mai Hospital, 78 Giai Phong, Dong Da, Hanoi, Vietnam 4 L’Hôpital Français de Hanoi, 1 Dong Da, Hanoi, Vietnam Received 29 April 2019 Revised 06 May 2019; Accepted 21 June 2019 Abstract: This descriptive study describes the clinical, paraclinical characteristics in children with renal tubular acidosis. In this study, 36 children with renal tubular acidosis were hospitalized in the National Hospital of Pediatrics from June, 2012 to July, 2017. Among the patients, were male; the male/female ratio was . The average age of the patients was ± years. There were 29 type 1 renal tubular acidosis patients () and 7 type 2 renal tubular acidosis (). The most common clinical signs were slow weight gain (100%), polyuria and vomiting were , excessive water drinking (), diarrhea (), weak lower limb (), and apnea (). The laboratory values on admission were: blood pH ± ; HCO3- ± ; serum sodium 136 ± 7mmol/l; potassium ± mmol/l; chloride 112 ± 9 mmol/l. The study concludes that of the clinical, paraclinical characteristics in children with Renal Tubular Acidosis were inconspicuousness, which effected the children’s growth. The study recommends a long-term strategy for diagnosis and follow–up treatment of renal tubular acidosis. Keywords: Renal tubular
