Shrimp farming plays a key role in economy of many countries all over the world. Unfortunately, a disease called Acute Hepatopancreatic Necrosis Disease (AHPND) or Early Mortality Syndrome (EMS) caused by Vibrio parahaemolyticus spreading from Asia to Central America costs shrimp industry billions of dollars annually. In the past few years, scientists from multi-disciplinary field collaborated to find out a solution for this disease. Until now, there are not any effective approaches to prevent and cure this disease | Potential growth inhibition activity of fecal materials, mucus and cultured water of tilapia Oreochromis niloticus on Acute Hepatopancreatic Necrosis Disease (AHPND) - causing pathogen Vibrio parahaemolyticus