PAHs được biết đến là hợp chất ô nhiễm hữu cơ độc hại, khó phân hủy được sinh ra từ quá trình đốt cháy không hoàn toàn các vật chất hữu cơ bao gồm việc hút thuốc. Để đánh giá sự tiếp nhiễm PAHs qua thói quen hút thuốc, 16 PAHs trong mẫu tóc của 32 người hút thuốc và 20 người không hút thuốc được phân tích sử dụng phương pháp sắc kí khí ghép nối khối phổ. | Xác định hàm lượng PAHs trong mẫu tóc của người hút thuốc và người không hút thuốc sử dụng phương pháp sắc kí khí ghép nối khối phổ VNU Journal of Science: Natural Sciences and Technology, Vol. 35, No. 3 (2019) 108-117 Original Article Determination of PAHs content in hair samples of smokers and non-smokers using gas chromatography in hyphenation with mass spectrometry Phung Thi Vi, Nguyen Thuy Ngoc, Truong Thi Kim, Nguyen Thi Quynh, Duong Hong Anh, Pham Hung Viet Research Centre for Environmental Technology and Sustainable Development, VNU University of Science, 334 Nguyen Trai, Hanoi, Vietnam Received 13 June 2019 Revised 11 July 2019; Accepted 12 July 2019 Abstract: PAHs are known as toxic, persistent organic pollutants produced by incomplete combustion of organic materials including smoking. To assess the exposure of PAHs through smoking habits, 16 PAHs in hair samples of 32 smokers and 20 non-smokers were analyzed using gas chromatography in hyphenation with mass spectrometry. The results showed that total content of PAHs in hair samples of smokers ranged from ng/g to 1,257 ng/g (mean: ng/g) and that of non-smokers ranged from ng/g to ng/g (mean: ng/g). Application of the Student statistical method indicated that the dataset of PAHs in hair samples between two subject groups were significantly different. Phenanthrene, pyrene, fluoranthene were the most dominant PAHs in hair samples of both smokers and non-smokers. The mean content of total toxicity equivalent of 16 PAHs compared to benzo (a) pyrene in hair samples of smokers and non-smokers were ng/g and ng/g, respectively. Some considerable values of PAHs including PAH4, PAH8 and BaPeq were higher than other similar studies in the world except one study in Japan. The analysis of PAHs in a new biomarker such as hair samples is a potential research trend to assess the exposure of PAHs in the human body.
