To evaluate the feasibility and the effect of the laparoscopic debulking surgery in the treatment of advanced ovarian cancer after neoadjuvant chemotherapy. Subjects and methods: We performed a retrospective review of laparoscopic approach in patients with histologically confirmed epithelial ovarian cancer (International Federation of Gynaecology Obstetrics staged IIIC-IV) who received 3 courses of neoadjuvant chemotherapy, from January 2012 to January 2018, at Department of Obstetrics and Gynaecology, Hue Central Hospital. Results: A total of 32 patients were included. The median age was 51 years (range, 25 - 67 years), median body mass index was kg/m2 (range, 20 - 41 kg/m2 ). All patients had good clinical response to 3 cycles of neoadjuvant chemotherapy. Most women underwent a complete debulking surgery with no residual disease (). The median operation time was 150 minutes (range, 75 - 330 minutes), the median blood loss was 85 mL (range, 55 - 220 mL). The median number of removed pelvic lymph nodes was 14 (range, 09 - 21). There was one intraoperative complication () and two postoperative short-term complications (). The median length of hospital stay was 5 days (range, 4 - 13 days). The median follow-up was 18 months (range, 5 - 56 months). | Evaluation of the results of laparoscopic debulking surgery in the management of advanced ovarian cancer after neoadjuvant chemotherapy at Hue Central Hospital