To determine the prevalence of depression disturbances and factors related to depression of 457 high school students in Danang City. Methods: Cross-sectional study and using DASS 42 scale. Results: The incidence of depression among high school students in Danang was , including mild, moderate, severe and very severe levels (, and , respectively). Friends and living conditions, family conflicts, isolation of friends, study pressures, self-targeting, feelings of inferior to friends and using alcohol are all related to depression (p | The current depression situation of public high school students in Danang city