The guest-host interaction between Dapsone drug and β-cyclodextrin (β-CD) was investigated using fluorescence spectroscopy, 1 H-NMR, and liquid chromatography with fluorescence detection. The optimized conditions for the interaction were investigated by spectrofluorometry and were found to be at mg/mL ( mM) of β-CD and pH . For these conditions, very low concentration of Dapsone drug of ng/mL ( nM) can be detected. | An undergraduate experiment using cyclodextrin – assisted sensitive fluorescence detection and quantitation of dapsone drug in wastewater samples
