In a previous report, we demonstrated the presence of cells with a neural/glial phenotype on the concave side of the vertebral body growth plate in Idiopathic Scoliosis (IS) and proposed this phenotype alteration as the main etiological factor of IS. In the present study, we utilized the same specimens of vertebral body growth plates removed during surgery for Grade III–IV IS to analyse gene expression. | A new look at causal factors of idiopathic scoliosis: Altered expression of genes controlling chondroitin sulfate sulfation and corresponding changes in protein synthesis in vertebral body growth plates
