Clinical studies have shown that applying pulsed radiofrequency (PRF) to the neural stem could relieve neuropathic pain (NP), albeit through an unclear analgesic mechanism. And animal experiments have indicated that calcitonin gene-related peptide (CGRP) expressed in the dorsal root ganglion (DRG) is involved in generating and maintaining NP. | Pulsed radiofrequency applied to the sciatic nerve improves neuropathic pain by down-regulating the expression of calcitonin gene-related peptide in the dorsal root ganglion
