Nitrogen (N) and sulphur (S), being essential macronutrients, have important roles in microalgae metabolism. Effects of N- or S -shortage were investigated in the green microalgae Chlorella s o-rokiniana subjected to 24 h of starvation, by measuring the glutamine synthetase (GS) and O-ace - tylserine(thiol)lyase (OASTL) activities, p roteins and amino acids levels. To test possible met a-bolic impact related to carbon (C) metabolism in response to N- or S -deprivation, starch and total C, N and S contents were also determin ed. The growth of C. sorokiniana cells was affected by N or S availability. The algae cultured for 24 h in a medium deprived of nitrogen or sulphur showed a decrease in the growth rate and changes in the average volume cell. Nitrogen starvation affected proteins level in the algae cells more than S-deprivation did. | Cross-Effects of Nitrogen and Sulphur Starvation in Chlorella sorokiniana 211/8K