Adeno-associated virus (AAV) vectors have been utilized extensively in gene therapy and gene function studies, as strong transgene expression is a prerequisite for positive outcomes. AAV8 was reported as the most efficient AAV serotype for transduction of the liver, brain and muscle compared with other serotypes. | Enhancing transgene expression from recombinant AAV8 vectors in different tissues using woodchuck hepatitis virus post transcriptional regulatory element