Circulating microRNAs (miRNAs) play critical roles in pathogen–host interactions. Aberrant miRNA expression profiles might have specific characteristics for virus strains, and could serve as noninvasive biomarkers for screening and diagnosing infectious diseases. In this study, we aimed to find new potential miRNA biomarkers of hepatitis C virus (HCV) infection. | Dysregulated serum MicroRNA expression profile and potential biomarkers in hepatitis C virus-infected patients