Host immune pressure and associated immune evasion of pathogenic bacteria are key features of host-pathogen co-evolution. Human T-cell epitopes of Mycobacterium tuberculosis (M. tuberculosis) were evolutionarily hyperconserved and thus it was deduced that M. tuberculosis lacks antigenic variation and immune evasion. | Single nucleotide polymorphism in AG85 genes of Mycobacterium tuberculosis complex: Analysis of 178 clinical isolates from china and 13 BCG strains