Urinary tract infections (UTIs) are one of the most common bacterial infections encountered in clinical practice. The knowledge of etiology and antibiogram of uropathogens helps in starting empirical treatment till the results of antibiotic susceptibility is awaited. Therefore this two year retrospective study was undertaken to determine the bacteriology and antimicrobial susceptibility pattern of UTIs in a tertiary care hospital. Urine samples from patients suspected of having UTI were processed according to standard microbiological techniques. Bacterial pathogens were isolated, identified and antimicrobial susceptibility testing was done by Kirby Bauer Disc Diffusion from 286 culture positive samples. Escherichia coli with 186(65%) isolates was predominant followed by Klebsiella pneumoniae 30(), Pseudomonas aeruginosa 20(7%), Enterococcus spp. 13(), Proteus spp. 10(), Acinetobacter spp. 8(), Staphylococcus aureus 7() and Coagulase negative Staphylococci (CoNS) 6(). Antibiogram of these bacteria suggests that empirical therapy to cover gram negative bacteria can be started with imipenem or piperacillin /tazobactum or nitrofurantoin. In selected cases vancomycin or linezolid can be added to give gram positive coverage. But in view of the increasing drug resistance antimicrobial susceptibility should be done and definitive therapy started immediately. | Bacteriological profile and antibiogram of uropathogens from a tertiary care hospital: A two year retrospective analysis
