Mites pose an increasing threat to grape cultivation in grape growing areas in Telangana and Andhra Pradesh causing heavy loss in the field. Mites which are minor pests earlier in grapes have become serious, particularly before harvest of the crop in the recent years. Two species viz., Tetranychus urticae, and Eutetranychus orientalis are found causing damage to grapevine both in Telanagna and Andhra Pradesh. Among them, the two spotted red spider mite T. urticae causes severe loss. The present studies on population dynamics of mites in grape and their management were conducted at Grape research station, Rajendranagar, Hyderabad, during 2011-13. Studies on management of mites in grape were conducted in a completely randomized block design with seven treatments. The treatments include Abamectin @ ml/l, Dicofol @ 2 ml/l, Sulphur @ 2 g/l, Fenpyroximate @ 1 ml/l, Spirotetramat @ ml/l, Difenthurion 50 SC @ ml/l and Control. Among the tested treatments Abamectin @ ml/l was effective in the management of mites with percent reduction of mites over control followed by Spirotetramat @ ml/l with percent reduction of mites over control. During 2012- 13 Abamectin was effective followed by Spirotetamat@ with and percent reduction over control respectively after 10 days of second spray. High volume with high pressure water sprays help to reduce the dust and water stress. Increase the humidity in vineyard and also dislodge the mites from foliage thereby temporarily reducing the mite population.