Protein accounts for the major requirement of the human body, as the Dietary Reference Intake (DRI) of protein is kilogram of body weight. The Indians have been reported deficient of major amino acids according to the surveys conducted in recent years. Single cell protein (SCP) represents microbial cells grown in mass culture that are harvested as dried cell mass in the form of natural protein concentrate. In the present studies apple, orange, tomato and pea peels were used as the substrate to grow Saccharomyces cerevisiae strains to obtain single cell protein. On estimating the protein obtained by Lowry‟s method the maximum quantity was milligrams per milliliter (mg/ml) from pea peels and thin-layer chromatography (TLC) confirmed it to be a good mixture of essential and non-essential amino acids. | Production of single cell protein from fruit and vegetable waste using Saccharomyces Cerevisiae