Pseudomonas aeruginosa are established pathogens predominantly in various nosocomial infections which are often life threatening due to limited therapeutic options. The present study was undertaken to analyze the antibiotic susceptibility pattern in the clinical isolates of Pseudomonas aeruginosa, so as to establish the current therapeutic options available for treatment in this geographical area of North East India. The study was conducted on 150 strains of Pseudomonas aeruginosa isolated from various clinical samples. Isolation and confirmation of the organism in culture was performed using standard microbiological techniques. The antibiotic susceptibility testing was performed by Kirby Bauer Disc diffusion method. Out of all clinical samples were identified to be Pseudomonas aeruginosa and were elderly male patients. The highest numbers () of isolates were from pulmonary samples like sputum, Endotracheal aspirate and Bronchoalveolar lavage, followed by urine (). isolates were resistant to Imipenem, followed by Meropenem (), Piperacillin Tazobactum (14%) and Piperacillin (). Higher level of resistance was observed with Nitrofurantoin(), Gentamicin (), Amikacin (42%), Ciprofloxacin (46%) and Levofloxacin (42%). A total of 43() isolates were Multi-Drug resistant. In our hospital, the antibiotic of choice for treatment of infections due to Pseudomonas aeruginosa could be Piperacillin Tazobactum. Emphasis on strict adherence to hospital infection control guidelines and antibiotic policy is also recommended as most of the isolates were recovered from hospitalized patients. | Antibiotic susceptibility pattern in clinical isolates of Pseudomonas aeruginosa from a tertiary care hospital of Tripura
