In this study is presented the influence of different plant’s pollen grains on the spread of allergic diseases in people sensitive to allergic factor living in Elbasan region of Albania for 2018. To achieve this goal, allergy tests have been performed by prick test on a number of individuals who have shown signs of allergies. 10 plant alergenes (Alnus glutinosa, Artemisia vulgaris, Ambrosia sp., Betula pendula, Corylus avellana, Parietaria officinalis, Phleum pratense, Platanus orientalis, Quercus sp., Secale cereale) were used and the variability of allergenic disease by pollen was studied by age group, place of residence, gender and months of the year. From the study it turned out that the worst affected age group is 20-30 years old; the largest number of allergy sufferers was in the city, Alnus glutinosa was the main cause of the allergic diseases and the largest number of people suffering during the spring seasons.