Diabetic foot ulcer is a major complication of diabetes mellitus, and probably the major component of the diabetic foot. Wound healing is an innate mechanism of action that works reliably most of the time. The present study was carried out in Department of Microbiology, in a tertiary care hospital, over a period of one year from June 2016 – May 2017. 50 diabetic patients with foot ulcer attending the Surgery Out Patient Department were included in the study. These patients were diabetic or detected to be diabetic by blood glucose estimation at the time of their visit to the hospital. In the present study, Of the 50 cases studied, most of the patients belonged to > 60 years of life. Males were more affected compared to females with a ratio . Among Gram positive aerobes, Staphylococcus aureus was the predominant isolate () followed by Enterococcus faecalis in of cases. Among Gram negative aerobes, Proteus mirabilis was the most common isolate () and followed by Pseudomonas aeruginosa and Klebsiella pneumoniae in of the cases. | The microbiology of diabetic foot ulcer infections - Prospective study