K. pneumoniae is responsible for a wide variety of hospital and community-acquired infections, affecting patients with normal immune systems as well as those with pre-existing conditions. The Carbapenems are β-lactam antibiotics that are used in the treatment of infections caused by Extended Spectrum beta-Lactamases (ESBL) producing gram negative bacteria (GNB). Carbapenem antibiotics are considered the drugs of choice for the treatment of ESBL -producing Enterobacteriaceae and other multidrug resistant bacteria. However, resistance to carbapenems is being increasingly detected and is mainly related to the action of carbapenemase-type enzymes. The emergence of bacterial strains that produce carbapenemases further limits the therapeutic options available to clinicians. Genotying of carbapenem resistant Klebsiella pneumoniae from clinical isolates. This was a hospital based prospective study, undertaken in the department of Microbiology. All clinical isolates like Urine, Pus, ET secretions, BAL, Blood and other Body fluids received in the laboratory were subjected to routine processing as per standard procedures. Identification &Antimicrobial susceptibility testing was performed by Vitek2 system. Modified Hodge test was carried out as confirmatory test. | Genotying of carbapenem resistant klebsiella pneumoniae from clinical isolates
