The second generation antipsychotic drug risperidone is widely used in the field of child and adolescent psychiatry to treat conditions associated with disruptive behavior, aggression and irritability, such as autism spectrum disorders. While risperidone can provide symptomatic relief for many patients, there is considerable individual variability in the therapeutic response and side-efect profle of the medication. | A systematic review of the effects of CYP2D6 phenotypes on risperidone treatment in children and adolescents