This study aims to investigate the extent and factors that influence on the response to depression of Buddhists. The study was conducted on 150 Buddhists, 78 of them male and 72 female. Buddhists between the ages of 18 and 25, who are pupils, students or have been working. The results of the study show that, overall, the depression level of Buddhist monks in this study was lower than the level of youth depression in some of the available studies. Of these, the women have higher levels of depression than men. In addition, working-class Buddhists have slightly higher levels of depression than those who are unemployed and educated. | Levels and factors affect on the response to depression of buddhist in Hue city