During the first three months of pregnancy, the developing embryo may be susceptible to external and internal factors, which may lead to structural and functional congenital anomalies. The main objective of this study was to determine the prevalence of congenital anomalies in Addis Ababa and the Amhara region, Ethiopia. | Congenital anomalies prevalence in Addis Ababa and the Amhara region, Ethiopia: A descriptive cross-sectional study