Biofortification is a promising, economical, and sustainable technique of providing micronutrients. It primarily targets population that has mainly dependent upon major food crops which are unfortunately poor sources of micronutrients. In developing countries, more than 20 million farm families are now growing and consuming biofortified crops. Here we described history of Biofortification, it‘s three different methods namely transgenic, breeding and agronomic and efforts to review different Biofortification research. Biofortification research based on different nutrient, different strategies and conducted on different crops. Address advantages and disadvantages of Biofortification and quote that besides challenges biofortified crop embrace bright future to challenge malnutrition.