The study was carried out to assess the status of Mycoplasmosis in goats by serology, of Mycoplasma spp. from suspected and apparently normal goats and to assess the epidemiological risk factors associated with Mycoplasmosis and economic impact of Mycoplasmosis in organised and unorganised goat farms present in North West Agroclimatic zone of Tamil nadu. Seroprevalence of Mycoplasmosis was assessed by employing slide agglutination test and iELISA. A total of 336 serum samples were collected from organised (122) and unorganised (244) goat farms. High seropositivity was observed in more than 2 years of age group, adult females, particularly breed of Salem black. Animals in intensive system of rearing and located in urban areas shown higher seropositivity. High incidence of Mycoplasmosis was observed in higher in summer months and thatched roofing system. | Epidemiological and economical study on Mycoplasmosis in goats in Tamil Nadu, India