Diarrhoea is one of the most important problem causing great economic loss to dairy industry by drastic reduction in milk production. The present study was carried out in cattle reared at different organized dairy farms in and around Durg to evaluate the therapeutic efficacy of synbiotics along with antibiotic in diarrhoeic cattle. A total of 18 cattle were selected and divided into three groups. Group I (n=6) served as normal healthy control whereas group (n=6) II and III were diarrhoeic cattle. Group II animals were treated with ciprofloxacin @ 5 mg/kg orally twice daily for 5 days and Group III were administered with combination of ciprofloxacin@ 5 mg/kg orally BID for 5 days and symbiotic (Ecotas® ) two boli orally OD for 5 days. Escherichia coli () was found to be most common pathogen involved in cattle diarrhoea followed by Salmonella spp. () and Proteus spp. () respectively. The hemato-biochemical alterations revealed significant increase in haemoglobin, PCV, TEC, TLC, neutrophils, total protein, albumin, albumin: globulin ratio and potassium values whereas, there was a significant decrease in lymphocyte, monocyte, eosinophil, globulin, sodium and glucose levels which returned near to normal values over the due course of treatment period in Group III followed by Group II. Rumen function profile revealed significant decrease in rumen pH, sedimentation activity time and protozoan motility values, while cellulose digestion and methylene blue reduction values were increased in diarrhoeic cattle. The rumen function profile returned to normal in Group III followed by Group II. Hence, combination of antibiotic along with symbiotic proved to be a better alternative when compared to antibiotic alone for therapeutic management of diarrhoea in cattle. | Efficacy of synbiotics as an adjunct to antibiotic therapy in Diarrhoeic cattle
