Enteric fever is a global health problem and is also endemic in India. The etiologic agents of enteric fever . S. typhi and S. paratyphi occurs mostly through food-borne or waterborne transmission. Worldwide, however, there are an estimated 22 million cases of enteric fever annually, with 600,000 deaths and an estimate of the annual typhoid incidence rate of per 100,000 person years was reported from India in 2008. The laboratory diagnosis of enteric fever is very important mainly in this post-antibiotic era. Isolation of Salmonella by blood culture is proof that the patient has a salmonella septicemia and still is the definitive diagnosis for a patient. Antibiotic therapy is the only effective treatment for enteric fever. Currently, fluoroquinolones and third generation cephalosporins are drugs of choice for treatment of typhoid fever though recent reports of decreased susceptibility to these agents and emergence of resistance to chloramphenicol, ampicillin and cotrimoxazole have led to the prospect of reemergence of untreatable typhoid fever and an increasing global burden. A total of 110 nos. of blood samples were collected from patients (cases) clinically suspected of Enteric fever for a duration of one year from August’2016-July’ 2017. Salmonella isolation was done by conventional methods of culture. Species identification was done by KBO11. | Study of salmonella isolates and their antimicrobial susceptibility pattern in a tertiary care hospital of NE-India
