A field experiment was conducted during the winter season of 2016-17 and 2017-18 at Agricultural Research Station (MPUAT), Banswara (Rajasthan), India to find out effective weed management strategy for enhancing the economical return of winter maize under humid condition of Southern Rajasthan. Ten treatment combinations of pre-emergence (atrazine), post-emergence (halosulfuron, 2, 4-D, tembotrione and topramezone) herbicides with weed free and weedy check laid out in randomized block design with three replications. Results revealed that pre-emergence application of atrazine 50 WP @ kg fb post emergence application of tembotrione 42 SC @ 120 g at 35 DAS reduced the density of grasses, broad leaves and sedge weeds and improved the growth and yield attributes of the crop. The highest yield ( t/ha) and lowest weed index were recorded with weed free followed by grain yield ( t/ha) and weed index () of the treatment of atrazine 50 WP @ kg PE fb tembotrione 42 SC @ 120 g PoE. The highest net return ($2095/ha) recorded with atrazine PE fb tembotrione PoE followed by weedy free ($2011/ha). However, maximum B: C ratio () recorded with pre-emergence application of atrazine 50 WP @ kg fb post-emergence application of tembotrione 42% SC @ 120 g/ha following by tembotrione 42 SC @ 120 g PoE alone (), which was significantly higher over rest treatments. Atrazine 50% WP @ kg ha PE fb tembotrione 42 SC @ 120 g PoE was found best among the herbicidal treatments in all respects. Hence, sequential application of atrazine 50 WP @ kg PE fb tembotrione 42 SC @ 120 g PoE at 35 DAS may be recommended for higher economic return through effective weed management in winter maize under humid condition of Southern Rajasthan. | Effective weed management strategy for winter maize (Zea mays L) under humid condition of southern Rajasthan, India