Tuberculosis (TB) is the commonest opportunistic infection and cause of death in patients with Human Immunodeficiency Virus (HIV) in developing countries. World Health Organization (WHO) recommends 85% treatment success rate for all TB cases as an indicator of TB control. The study aimed at determining TB co infection among the seropositive cases. It was a cross-sectional study among seropositive patients whose sociodemographic characteristics with treatment history were obtained using a semi-structured questionnaire. Sputum samples were collected and tested for acid-fast bacilli (AFB) using a standard method according to national guideline for TB treatment to determine treatment success rate. Treatment success was defined as any HIV positive patient with a diagnosis of TB by acid-fast bacilli (AFB) smear positivity at diagnosis, who after 6 months of complete treatment becomes smear negative. A total of 209 HIV patients were enrolled for this study. Fifty-nine () were females, 106 () were newly treated for TB. Eighty-five () were treated in a government health facility. A total of 29 had tested positive for tuberculosis using Gene xpert and ZN microscopy. In our study we found 29 cases of tuberculosis among 209 seropositive patients which is . | The incidence of tuberculosis and various factors associated with tuberculosis in seropositive patients