Retinopathy of prematurity (ROP) still represents one of the leading causes of visual impairment in childhood. Systemic propranolol has proven to be effective in reducing ROP progression in preterm newborns, although safety was not sufficiently guaranteed. | Study protocol: Safety and efficacy of propranolol eye drops in newborns with a precocious stage of retinopathy of prematurity (): A multicenter, open-label, single arm, phase II trial