Hemophagocytic lymphohistiocytosis (HLH) is a rare, life-threatening disorder characterized by prolonged fever, cytopenia, hepatosplenomegaly, rash, icterus, and other neurological symptoms. Successful treatment of HLH by etoposide has improved outcomes for children with HLH. | Acute myeloid leukemia following etoposide therapy for EBV-associated hemophagocytic lymphohistiocytosis: A case report and a brief review of the literature