A healthy, productive and well-motivated workforce is the key agent for overall socioeconomic development. To assess the health of leather industry workers, selection of nine leather industries from Kanpur was done purposively by taking a sample of three units each from leather processing, leather production and combined leather units having both leather processing and production. Similarly, 90 workers were selected randomly, taking 30 each from selected three leather units to assess their health hazards. Structured interview schedule was used for data collection. Survey was carried out to collect the desired information. Frequency, percentage were used to analyze the data. Findings revealed that majority of the leather units were located in Jajmau area of Kanpur. Regarding profile of workers highlights that majority () of respondent were in the age group of 41-45 years, educated upto primary level (). Majority of the respondents () had smoking habit. Researcher found that percent respondents of leather processing units, percent respondents of leather production units and 80 percent respondents of combine leather units had no past record of any health issues/illness. Majority of the respondents () family members did not suffer from any disease which is hereditary by nature.