Study was conducted on 84 adult male Wistar rats for duration of sixty days. Animals were divided into twelve equal groups and treatments were applied as 2x3x2 factorial design with 2 renal conditions (Normal and Compromised); 3 cholesterol supplementation levels (0%, and 1% w/w on DM basis) and 2 niacin supplementation levels (Unsupplemented and Supplemented @ 100 mg/kg body weight per day orally). Renal dysfunction was induced in respective groups by daily intra-peritoneal injection of gentamicin @ 80mg/kg body weight for 8 days. Blood samples were collected on 0th, 20th, 40th and 60th day of experiment to study lipid profile. | Effect of cholesterol and niacin supplementation on serum lipid profile in experimentally induced renal dysfunction in wistar rats
