There have been many studies supporting fluconazole prophylaxis in preterm infants for prevention of invasive fungal infections (IFIs). However, the routine use of fluconazole prophylaxis in neonatal intensive care units (NICUs) raises concerns with respect to resistance development, including the selection of resistant Candida species. | Efficacy and safety of fluconazole prophylaxis in extremely low birth weight infants: Multicenter pre-post cohort study